Our focus is on bacterial cell biology and the host response.
Research topics:
* Oral treponemes and Alzheimer's disease. The objective is to understand the influence of treponemes in the inflammatory process associated with Alzheimer's disease.
* Oral infection and risk factors for pancreatic cancer. We are investigating the importance of oral infection as a risk factor in patients with pancreatic cancer.
* Human Oral Microbiome Database (HOMD). We are providing a comprehensive data set of the genetic potential and phylogenetic diversity of oral bacteria to sustain the world research efforts on fastidious pathogens.
* Treponema denticola cytoplasmic filaments involvement in pathogenicity (CFPA). The objectives are to understand the implication of this intracellular structure in the pathogenicity of the bacteria at the infection site.
* Architecture and motility of Treponemes (FLA). To further our understanding of the cell architecture in dissemination we are examining the bacteria in its 3-dimensions, using tomography.
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